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Lastly, clonidine enhances neuraxial opioids and, together with fentanyl, interacts in an additive method, which could reduce the dose of every part by sixty% for postoperative analgesia.Jun 10, 2024 · If clonidine therapy will be to be replaced by a ?-blocker, delay administration of the ?-blocker for quite a few days after clonidine therapy has